With roots in United States, Mad Space Cow Disease takes part in Age of Empires II. 4 matches of Age of Empires II are on Mad Space Cow Disease's record. Mad Space Cow Disease is most active in the unranked ladder.

Mad Space Cow Disease prefers non-competitive gameplay and has never played ranked. Huns stands out as Mad Space Cow Disease's preferred civ with a 50.0% selection rate.